Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM50243908'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM50243908(CHEMBL4103586 | US10966980, Example 221)copy SMILEScopy InChI
Affinity DataIC50: 0.00900nMAssay Description:Test article and assay controls were added to a 384-well plate. Reaction mixtures contained 20 mM HEPES, pH 7.4, 10 mM magnesium chloride, 0.01% bovi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29S1V59US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM50243908(CHEMBL4103586 | US10966980, Example 221)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human JAK1 using 5'FAM-KKSRGDYMTMQID as substrate in presence of 1 mM ATP by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79DTWPubMed