Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM50392002'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Argenta Discovery Ltd.

Curated by ChEMBL
LigandPNGBDBM50392002(CHEMBL2152306)copy SMILEScopy InChI
Affinity DataKi:  45nMAssay Description:Inhibition of JAK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1KZXPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Argenta Discovery Ltd.

Curated by ChEMBL
LigandPNGBDBM50392002(CHEMBL2152306)copy SMILEScopy InChI
Affinity DataKi:  46nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) using Val-Ala-Leu-Val-Asp-Gly-Tyr-Phe-Arg-Leu-Thr-Thr as substrate after 30 mins in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4K40PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Argenta Discovery Ltd.

Curated by ChEMBL
LigandPNGBDBM50392002(CHEMBL2152306)copy SMILEScopy InChI
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL2-induced STAT3 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1KZXPubMed