Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM50402081'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50402081(CHEMBL2206619)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Inhibition of JAK1 kinase domain assessed as phosphorylation of N-terminal 5-carboxyfluorescein-tagged Val-Ala-Leu-Val-Asp-Gly-Tyr-Phe-Arg-Leu-Thr-Th...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PPPPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50402081(CHEMBL2206619)copy SMILEScopy InChI
Affinity DataEC50: >3.80E+3nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-induced STAT3 phosphorylation incubated for 20 mins prior to IL6-induction measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55PPPPubMed