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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM147860'
Target
Tyrosine-protein kinase JAK2
(Human)
Merck Sharp & Dohme Corp.
US Patent
Ligand
BDBM147860
(US8962608, 28-184)
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Affinity Data
IC50: 23nM
Assay Description:
The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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antibodypedia
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Ligand Info
PC cid
PC sid
Similars
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Details
BindingDB Entry DOI:
10.7270/Q2J101W0
US Patent