Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM185700'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Zoetis Services LLC

US Patent
LigandPNGBDBM185700(US10875847, Compound Oclacitinib | US9161939, 1a |...)copy SMILES
Affinity DataIC50: 17.5nMpH: 7.4Assay Description:Methods: A peptide mobility shift assay was used to quantify the phosphorylation of the JAKtide (JAK-2 and JAK-3) or the IRS-1 peptide (JAK-1 and Tyk...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC0ZF7US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Zoetis Services LLC

US Patent
LigandPNGBDBM185700(US10875847, Compound Oclacitinib | US9161939, 1a |...)copy SMILES
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant JAK2 (808 to 1132 residues) by Z-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27ZSZPubMed