Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM47170'
TargetTyrosine-protein kinase JAK2(Human)
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM47170(US8962608, 42-1 | US8962608, 42-4)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J101W0US Patent
TargetTyrosine-protein kinase JAK2(Human)
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM47170(US8962608, 42-1 | US8962608, 42-4)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J101W0US Patent
TargetTyrosine-protein kinase JAK2(Human)
Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM47170(US8962608, 42-1 | US8962608, 42-4)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J101W0US Patent