Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50343725'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50343725((S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5...)copy SMILEScopy InChI
Affinity DataKi:  0.450nMAssay Description:Inhibition of JAK2 V617F mutant (unknown origin) using L-Ahx-IPTSPITTTYFFFKKK-COOH as substrate in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79FW6PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50343725((S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of JAK2 after 60 minMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95ZDPubMed