Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50449380'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50449380(CHEMBL3126342)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant Jak2 (unknown origin) using biotinylated synthetic peptide substrate by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D22034PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50449380(CHEMBL3126342)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of Jak2 (unknown origin) assessed as inhibition of STAT5 phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D22034PubMed