Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM139691'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Pfizer Limited

US Patent
LigandPNGBDBM139691(US8895544, 1)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:JAK3 enzyme (Invitrogen) stock solution is made up at 4.1 uM in sterile water. JAK3 enzyme stock is diluted to 2 nM in assay buffer (10 mM HEPES free...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S46QNMUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Pfizer Limited

US Patent
LigandPNGBDBM139691(US8895544, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of GST tagged human recombinant JAK3 catalytic domain expressed in baculovirus using peptide substrate preincubated for 60 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0HDZPubMed