Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM202552'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202552((E)-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8S22PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202552((E)-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate in presence of 10 uM [gamma33P]ATP by radiometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard-Karls-University Tuebingen

LigandPNGBDBM202552((E)-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in baculovirus expression system assessed as reduction in polypeptide substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN6988PubMed