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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM228721'
Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
HUTCHISON MEDIPHARMA LIMITED
US Patent
Ligand
BDBM228721
(US10369153, Compound 80 | US9346810, 80)
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Affinity Data
IC50: 550nM
Assay Description:
JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Ligand Info
PC cid
PC sid
In Depth
Details
BindingDB Entry DOI:
10.7270/Q27W6FJK
US Patent