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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM26199'
Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical
Ligand
BDBM26199
(N-[4-(4-methylpiperazin-1-yl)phenyl]-3-phenyl-1H-p...)
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Affinity Data
IC50: 98nM
pH: 7.5 T: 2°C
Assay Description:
An ELISA assay was used to determine the ability of inhibitor to inhibit JAK3 RTK activity. The compounds were incubated with enzyme, 10 uM ATP, and ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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Ligand Info
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2S75DP0
PubMed