Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50245587' TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 3.34E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 insect cells using poly (Glu,T...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 5.18E+3nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of recombinant GST-tagged human JAK3 expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincubated for 1 ...More data for this Ligand-Target Pair
