Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50433601'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50433601(CHEMBL2381983)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of JAK3 (unknown origin) using biotinylated poly-EY peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JMXPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50433601(CHEMBL2381983)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of JAK3 TEL domain (unknown origin) transfected in mouse Ba/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9JMXPubMed