Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3 [811-1124]' and Ligand = 'BDBM50021655'
TargetTyrosine-protein kinase JAK3 [811-1124](Homo sapiens (Human))TBA
LigandPNGBDBM50021655(DECERNOTINIB | US10112907, Example 00017 | US10766...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetTyrosine-protein kinase JAK3 [811-1124](Homo sapiens (Human))TBA
LigandPNGBDBM50021655(DECERNOTINIB | US10112907, Example 00017 | US10766...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent