Found 5 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM50469353' TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of N-terminal GST-tagged human MERTK cytoplasmic domain (528 to 999 end residues) expressed in baculovirus expression system using fluorec...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of N-terminal GST-tagged MERTK (528 to 999 residues) (unknown origin) cytoplasmic domain expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of MERTK in human 697 cells assessed as reduction in phosphorylated MERTK level preincubated for 1 hr followed by pervanadate phopshatase ...More data for this Ligand-Target Pair
