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TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of AXL (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST-tagged human AXL cytoplasmic domain (464 to 885 end residues) expressed in baculovirus expression system using fluorecen...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST-tagged AXL (464 to 885 residues) (unknown origin) cytoplasmic domain expressed in Sf21 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of AXL (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
UNC Eshelman School of Pharmacy
Curated by ChEMBL
UNC Eshelman School of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 859nMAssay Description:Inhibition of AXL in human A549 cells assessed as reduction in phosphorylated AXL level preincubated for 1 hr followed by pervanadate phopshatase inh...More data for this Ligand-Target Pair
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