Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 1' and Ligand = 'BDBM50075312'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
NIH

Curated by ChEMBL
LigandPNGBDBM50075312((Difluoro-naphthalen-2-yl-methyl)-phosphonic acid ...)copy SMILEScopy InChI
Affinity DataKi:  1.79E+5nMAssay Description:Binding affinity of the compound towards recombinant human Protein-tyrosine phosphatase 1B was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22F7MV1PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
NIH

Curated by ChEMBL
LigandPNGBDBM50075312((Difluoro-naphthalen-2-yl-methyl)-phosphonic acid ...)copy SMILEScopy InChI
Affinity DataKi:  1.79E+5nMAssay Description:Inhibitory activity against Yersinia Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B5ZDVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
NIH

Curated by ChEMBL
LigandPNGBDBM50075312((Difluoro-naphthalen-2-yl-methyl)-phosphonic acid ...)copy SMILEScopy InChI
Affinity DataKi:  1.97E+5nMAssay Description:Compound was evaluated for inhibitory constant against PTP1BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TD9XV0PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
NIH

Curated by ChEMBL
LigandPNGBDBM50075312((Difluoro-naphthalen-2-yl-methyl)-phosphonic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930V2PPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
NIH

Curated by ChEMBL
LigandPNGBDBM50075312((Difluoro-naphthalen-2-yl-methyl)-phosphonic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q232008TPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
NIH

Curated by ChEMBL
LigandPNGBDBM50075312((Difluoro-naphthalen-2-yl-methyl)-phosphonic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+4nMAssay Description:Compound was evaluated for 50% inhibition of PTP1B using uM)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TD9XV0PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
NIH

Curated by ChEMBL
LigandPNGBDBM50075312((Difluoro-naphthalen-2-yl-methyl)-phosphonic acid ...)copy SMILEScopy InChI
Affinity DataIC50: 7.18E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K49DWPubMed