Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
Found
5
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM384117'
Target
Tyrosine-protein phosphatase non-receptor type 11
(Homo sapiens (Human))
TBA
Ligand
BDBM384117
(1-(3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazi...)
copy SMILES
copy InChI
Affinity Data
IC50: 11nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2JS9VC6
PubMed
PDB
3D Structure (crystal)
Target
Tyrosine-protein phosphatase non-receptor type 11
(Homo sapiens (Human))
TBA
Ligand
BDBM384117
(1-(3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazi...)
copy SMILES
copy InChI
Affinity Data
IC50: 16nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q26977NN
PubMed
PDB
3D Structure (crystal)
Target
Tyrosine-protein phosphatase non-receptor type 11
(Homo sapiens (Human))
TBA
Ligand
BDBM384117
(1-(3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazi...)
copy SMILES
copy InChI
Affinity Data
IC50: 47nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2JS9VC6
PubMed
PDB
3D Structure (crystal)
Target
Tyrosine-protein phosphatase non-receptor type 11
(Homo sapiens (Human))
TBA
Ligand
BDBM384117
(1-(3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazi...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
In Depth
Details
BindingDB Entry DOI:
10.7270/Q28056F9
US Patent
PDB
3D Structure (crystal)
Target
Tyrosine-protein phosphatase non-receptor type 11
(Homo sapiens (Human))
TBA
Ligand
BDBM384117
(1-(3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazi...)
copy SMILES
copy InChI
Affinity Data
Kd: 49nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
PDB
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2JS9VC6
PubMed
PDB
3D Structure (crystal)