Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 22' and Ligand = 'BDBM50031906'
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031906(CHEMBL3360905)copy SMILEScopy InChI
Affinity DataKi:  2.87E+3nMAssay Description:Competitive inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6TVJPubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031906(CHEMBL3360905)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of N-terminal His-tagged Lyp (unknown origin) catalytic domain (1 to 294 residues) expressed in Escherichia coli BL21 (DE3) assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6TVJPubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50031906(CHEMBL3360905)copy SMILEScopy InChI
Affinity DataEC50:  6.49E+3nMAssay Description:Inhibition of Lyp in antiCD3-antibody-stimulated human Jurkat T cells assessed as activation of TCR-mediated and IL-2 promoter driven NFAT/AP1 transc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6TVJPubMed