Found 12 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 6' and Ligand = 'BDBM50391109'
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human recombinant GST-tagged SHP1 (catalytic domain 244 to 570 residues) expressed in Escherichia coli BL21 (DE3) using pNPP as substra...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of SHP1 (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of human GST-tagged SHP1 (244 to 570 residues) expressed in Escherichia coli BL21-CondenPlus (DE3) using pNNP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of SHP1 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of SHP1 (unknown origin) using 3-o-methylfluorescein phosphate as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of SHP1 (unknown origin) using 3-o-methylfluorescein phosphate as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.65E+4nMAssay Description:IC50 values were determined by pNPP assay.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of SHP1 (unknown origin) using pNPP as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of SHP-1More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of SHP1 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Yanbian University College of Pharmacy
Curated by ChEMBL
Yanbian University College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair