Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Ubiquitin-like modifier-activating enzyme ATG7' and Ligand = 'BDBM476165'
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476165(US10865208, Compound I-220 | {(2S,3S,5R)-5-[4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476165(US10865208, Compound I-220 | {(2S,3S,5R)-5-[4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B6366US Patent
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))TBA
LigandPNGBDBM476165(US10865208, Compound I-220 | {(2S,3S,5R)-5-[4-amin...)copy SMILEScopy InChI
Affinity DataIC50: 468nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DBRPubMed