Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Urotensin-2 receptor' and Ligand = 'BDBM50302271'
TargetUrotensin-2 receptor(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL
LigandPNGBDBM50302271((R)-2-(1-(3,4-dimethoxyphenyl)-4-(6-methoxypyrazin...)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Displacement of [125I]urotensin 2 from urotensin 2 receptor in human RMS13 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75GD7PubMed
TargetUrotensin-2 receptor(RAT)
Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL
LigandPNGBDBM50302271((R)-2-(1-(3,4-dimethoxyphenyl)-4-(6-methoxypyrazin...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75GD7PubMed
TargetUrotensin-2 receptor(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL
LigandPNGBDBM50302271((R)-2-(1-(3,4-dimethoxyphenyl)-4-(6-methoxypyrazin...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Antagonist activity at urotensin 2 receptor in human RMS13 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75GD7PubMed