Found 11 Enz. Inhib. hit(s) with Target = 'Urotensin-2 receptor' and Ligand = 'BDBM50459261' 
Affinity DataIC50: 5.40nMAssay Description:Displacement of [Na125I]-synthetic URP from human UT receptor expressed in HEK293 cell membranes incubated for 2 hrs by gamma-countingMore data for this Ligand-Target Pair
Affinity DataEC50: 7.20nMAssay Description:Antagonist activity at UT receptor in Sprague-Dawley rat thoracic aortic ring assessed as reduction in urotensin-2-induced contraction by measuring p...More data for this Ligand-Target Pair
Affinity DataEC50: 112nMAssay Description:Antagonist activity at UT receptor in Sprague-Dawley rat thoracic aortic ring assessed as reduction in URP-induced contraction by measuring pEC50 for...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Antagonist activity at UT receptor in Sprague-Dawley rat thoracic aortic ring assessed as reduction in urotensin-2-induced contraction by measuring p...More data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Antagonist activity at UT receptor in Sprague-Dawley rat thoracic aortic ring assessed as reduction in URP-induced contraction by measuring pEC50 for...More data for this Ligand-Target Pair
Affinity DataEC50: 29nMAssay Description:Agonist activity at UT receptor in Sprague-Dawley rat thoracic aortic ring assessed as induction of contractionMore data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Antagonist activity at UT receptor in Sprague-Dawley rat thoracic aortic ring assessed as reduction in URP-induced contraction by measuring pEC50 for...More data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Agonist activity at human UT receptor expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as induction of Gq activation ...More data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Agonist activity at human UT receptor expressed in HEK293 cells co-expressing G12-polycistronic BRET biosensor assessed as induction of G12 activatio...More data for this Ligand-Target Pair
Affinity DataEC50: 603nMAssay Description:Agonist activity at human UT receptor expressed in HEK293 cells co-expressing beta-arrestin1-polycistronic BRET biosensor assessed as induction of be...More data for this Ligand-Target Pair
Affinity DataEC50: 117nMAssay Description:Antagonist activity at UT receptor in Sprague-Dawley rat thoracic aortic ring assessed as reduction in URP-induced contraction by measuring pEC50 for...More data for this Ligand-Target Pair
