Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'Vasopressin V1b receptor' and Ligand = 'BDBM50205990'
TargetVasopressin V1b receptor(Homo sapiens (Human))
UMR7200 CNRS/Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50205990(CHEMBL395429 | OXYTOCIN)copy SMILEScopy InChI
Affinity DataKi:  1.78E+3nMAssay Description:Binding affinity to V1bR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB18KTPubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
UMR7200 CNRS/Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50205990(CHEMBL395429 | OXYTOCIN)copy SMILEScopy InChI
Affinity DataKi: >6.00E+3nMAssay Description:Displacement of [3H]AVP from human vasopressin V1b receptor expressed in HEK293 cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R6VPubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
UMR7200 CNRS/Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50205990(CHEMBL395429 | OXYTOCIN)copy SMILEScopy InChI
Affinity DataEC50:  39nMAssay Description:Agonist activity at human V1b receptor expressed in HEK293FT cells assessed as stimulation of calcium release by Aequorin based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0HRFPubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
UMR7200 CNRS/Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50205990(CHEMBL395429 | OXYTOCIN)copy SMILEScopy InChI
Affinity DataEC50:  29nMAssay Description:Agonist activity at human V1b receptor expressed in HEK293FT cells incubated for 30 mins by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0HRFPubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
UMR7200 CNRS/Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50205990(CHEMBL395429 | OXYTOCIN)copy SMILEScopy InChI
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human V1B receptor expressed in HEK293 cells assessed as intracellular calcium level measured at 3 secs interval for 5 mins by fu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87F60PubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
UMR7200 CNRS/Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50205990(CHEMBL395429 | OXYTOCIN)copy SMILEScopy InChI
Affinity DataEC50:  0.240nMAssay Description:Agonist activity at recombinant human V1b receptor expressed in HEK293 cells assessed as increase in intracellular calcium level measured at 3 secs i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0XXQPubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
UMR7200 CNRS/Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50205990(CHEMBL395429 | OXYTOCIN)copy SMILEScopy InChI
Affinity DataEC50:  240nMAssay Description:Agonist activity at human vasopressin V1b expressed in HEK293 cells after 5 hrs by firefly luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD426VPubMed
TargetVasopressin V1b receptor(Homo sapiens (Human))
UMR7200 CNRS/Universit£ de Strasbourg

Curated by ChEMBL
LigandPNGBDBM50205990(CHEMBL395429 | OXYTOCIN)copy SMILEScopy InChI
Affinity DataEC50:  33nMAssay Description:Agonist activity at human vasopressin V1b receptor expressed in CHO cells assessed as increase in intracellular calcium flux measured for 5 mins by F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0R6VPubMed