Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit alpha-1C' and Ligand = 'BDBM78577'
LigandPNGBDBM78577(BEPRIDIL HYDROCHLORIDE | Bepridil | MLS000028456 |...)copy SMILEScopy InChI
Affinity DataKi:  241nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5KP4PubMed
LigandPNGBDBM78577(BEPRIDIL HYDROCHLORIDE | Bepridil | MLS000028456 |...)copy SMILEScopy InChI
Affinity DataKi:  547nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GT5KP4PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Cavia porcellus)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM78577(BEPRIDIL HYDROCHLORIDE | Bepridil | MLS000028456 |...)copy SMILEScopy InChI
Affinity DataIC50: 211nMAssay Description:Inhibition of calcium current (ICaL) measured using whole-cell patch clamp experiments in isolated guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP264FPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Cavia porcellus)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM78577(BEPRIDIL HYDROCHLORIDE | Bepridil | MLS000028456 |...)copy SMILEScopy InChI
Affinity DataIC50: 211nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79D5CPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Cavia porcellus)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM78577(BEPRIDIL HYDROCHLORIDE | Bepridil | MLS000028456 |...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79D5CPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM78577(BEPRIDIL HYDROCHLORIDE | Bepridil | MLS000028456 |...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of L-type calcium channel measured using 2-electrode voltage-clamp in human embryonic kidney cells heterologically expressing alpha-1C sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79D5CPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Cavia porcellus)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM78577(BEPRIDIL HYDROCHLORIDE | Bepridil | MLS000028456 |...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79D5CPubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Ortho Pharmaceutical Corporation

Curated by ChEMBL
LigandPNGBDBM78577(BEPRIDIL HYDROCHLORIDE | Bepridil | MLS000028456 |...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of [3H]nitrendipine binding to calcium channels in Rabbit cardiac muscle.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72J19PubMed