Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'cAMP-dependent protein kinase catalytic subunit alpha' and Ligand = 'BDBM3149'
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Sphinx Laboratories

LigandPNGBDBM3149(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73BVVPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
A Division of Eli Lilly & Company

Curated by ChEMBL
LigandPNGBDBM3149(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration of the compound against recombinant human cAMP-dependent Protein kinase AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J965HRPubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Sphinx Laboratories

LigandPNGBDBM3149(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4V9M
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
A Division of Eli Lilly & Company

Curated by ChEMBL
LigandPNGBDBM3149(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)copy SMILEScopy InChI
Affinity DataKd:  3.90nMAssay Description:Binding affinity to PKAalpha (unknown origin) using Lys-Arg-Thr-Leu-Arg-Arg as substrate after 8 mins in presence of [gamma-32P]ATP by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348NB9PubMed