Found 6 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM14390' TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
BAYER AG
Curated by ChEMBL
BAYER AG
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
3D Structure (crystal)TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibitory concentration against phosphodiesterase 4 (PDE4) from rat kidneyMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
BAYER AG
Curated by ChEMBL
BAYER AG
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human recombinant PDE4 (Phosphodiesterase 4)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
BAYER AG
Curated by ChEMBL
BAYER AG
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of canine lung Phosphodiesterase 4 (PDE4)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
BAYER AG
Curated by ChEMBL
BAYER AG
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged human PDE4 expressed in baculovirus infected sf9 cells using [3H]cAMP as substrate measured after 30 mins by scin...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
BAYER AG
Curated by ChEMBL
BAYER AG
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against phosphodiesterase 4 (PDE4) isolated from canine lungMore data for this Ligand-Target Pair
