Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50495704'
LigandPNGBDBM50495704(Chf-6001 | Chf6001 | J3.309.618F)copy SMILEScopy InChI
Affinity DataIC50: 0.0260nMAssay Description:Inhibition of PDE4 in human U937 cell lysate using cAMP as substrate by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DVVPubMed
LigandPNGBDBM50495704(Chf-6001 | Chf6001 | J3.309.618F)copy SMILEScopy InChI
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5Z0DPubMed
LigandPNGBDBM50495704(Chf-6001 | Chf6001 | J3.309.618F)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE4 activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release after 18 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5Z0DPubMed