Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM130958'
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM130958(US8829010, 9)copy SMILEScopy InChI
Affinity DataIC50: 1.64nMAssay Description:In the present assay, the activity of the test substances on human full-length PDE2A3 enzyme was determined using the [3H]-cGMP scintillation proximi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PR7TNHUS Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM130958(US8829010, 9)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X06BK1PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM130958(US8829010, 9)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of full length recombinant human FLAG-tagged PDE2A3 expressed in sf21 cells using [3H]cGMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JNTPubMed