Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'cGMP-dependent protein kinase' and Ligand = 'BDBM50345726'
LigandPNGBDBM50345726(1-isopropyl-3-(4-isopropylphenyl)-1H-pyrazolo[3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K077GQUS Patent
LigandPNGBDBM50345726(1-isopropyl-3-(4-isopropylphenyl)-1H-pyrazolo[3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Kinase phosphorylation reactions were performed in a buffered medium containing 20 mM HEPES pH 7.5 (KOH), 0.1% BSA, 10 mM MgCl2, 1 mM EGTA (pH 7.2), ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K077GQUS Patent