Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B' and Ligand = 'BDBM50016839'
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50016839(5-Methyl-6-[4-(4,5,6,7-tetrahydro-benzoimidazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of phosphodiesterase 3 from human platelets at 1E-7-1E-4M or 1.0E-6 to 1E-3 MMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27083P1PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50016839(5-Methyl-6-[4-(4,5,6,7-tetrahydro-benzoimidazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against cAMP PDE III enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27S7MS4PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50016839(5-Methyl-6-[4-(4,5,6,7-tetrahydro-benzoimidazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S1857BPubMed