Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'eIF-2-alpha kinase GCN2' and Ligand = 'BDBM50011235'
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Dart Neuroscience LLC

Curated by ChEMBL
LigandPNGBDBM50011235(CHEMBL3260333)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of GCN2-mediated elF2alpha phosphorylation in human U2OS cells after 2 hrs by immunocytochemistryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ91XXPubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Dart Neuroscience LLC

Curated by ChEMBL
LigandPNGBDBM50011235(CHEMBL3260333)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of GCN2 (unknown origin) using GFP-elF2a as substrate preincubated with substrate for 20 mins measured after 90 mins by Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ91XXPubMed