Compile Data Set for Download or QSAR
Found 36 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 10429
TargetUromodulin(Human)TBA
LigandPNGBDBM534920(N′-cyano-N-((1,2,3,5,6,7-hexahydro-s-indacen...)copy SMILES
Affinity DataIC50: 1.26nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534906(US11236045, Example 42)copy SMILES
Affinity DataIC50: 2.40nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534843(US11236045, Example 34)copy SMILES
Affinity DataIC50: 3nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534862(US11236045, Example 39)copy SMILES
Affinity DataIC50: 3.30nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534910(US11236045, Example 48)copy SMILES
Affinity DataIC50: 3.5nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534921(N′-cyano-1-(4-cyanophenyl)-N-((1,2,3,5,6,7-h...)copy SMILES
Affinity DataIC50: 4nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534912(N′-cyano-N-((1,2,3,5,6,7-hexahydro-s-indacen...)copy SMILES
Affinity DataIC50: 4.40nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534905(US11236045, Example 41)copy SMILES
Affinity DataIC50: 4.80nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM50538416(CHEMBL4644835 | US11236045, Example 25)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534847(US11236045, Example 37)copy SMILES
Affinity DataIC50: 5.60nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM50538393(CHEMBL4647321 | US11236045, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534919(N′-cyano-2-fluoro-N-((1,2,3,5,6,7-hexahydro-...)copy SMILES
Affinity DataIC50: 7.70nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534918(N′-cyano-4-fluoro-N-((1,2,3,5,6,7-hexahydro-...)copy SMILES
Affinity DataIC50: 7.80nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM50538418(CHEMBL4641961 | US11236045, Example 54)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534813(US11236045, Example 17)copy SMILES
Affinity DataIC50: 12nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM50538407(CHEMBL4647621 | US11236045, Example 22)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534904(US11236045, Example 40)copy SMILES
Affinity DataIC50: 13nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534844(US11236045, Example 35)copy SMILES
Affinity DataIC50: 13nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534814(US11236045, Example 18)copy SMILES
Affinity DataIC50: 15nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534851(US11236045, Example 38)copy SMILES
Affinity DataIC50: 17nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534911(N′-cyano-N-((1,2,3,5,6,7-hexahydro-s-indacen...)copy SMILES
Affinity DataIC50: 19nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534839(US11236045, Example 26)copy SMILES
Affinity DataIC50: 23nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534909(N′-cyano-2,4-difluoro-N-((1,2,3,5,6,7-hexahy...)copy SMILES
Affinity DataIC50: 23nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534815(US11236045, Example 19)copy SMILES
Affinity DataIC50: 23nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534907(US11236045, Example 43)copy SMILES
Affinity DataIC50: 27nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM50538417(CHEMBL4643205 | US11236045, Example 55)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534840(US11236045, Example 27)copy SMILES
Affinity DataIC50: 27nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM50538421(CHEMBL4649141 | US11236045, Example 30)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534841(US11236045, Example 29)copy SMILES
Affinity DataIC50: 32nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534845(US11236045, Example 36)copy SMILES
Affinity DataIC50: 32nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534824(US11236045, Example 24)copy SMILES
Affinity DataIC50: 34nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534917(N′-cyano-3-fluoro-N-((1,2,3,5,6,7-hexahydro-...)copy SMILES
Affinity DataIC50: 38nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM50538420(CHEMBL4636825 | US11236045, Example 56)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534913(N′-cyano-N-((1,2,3,5,6,7-hexahydro-s-indacen...)copy SMILES
Affinity DataIC50: 45nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534822(US11236045, Example 21)copy SMILES
Affinity DataIC50: 62nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent
TargetUromodulin(Human)TBA
LigandPNGBDBM534908(US11236045, Example 44)copy SMILES
Affinity DataIC50: 63nMAssay Description:THP1 (Tamm-Horsfall Protein 1) monocytes were differentiated with PMA (Phorbol 12-myristate 13-acetate) (100 ng/ml) and incubated at 37° C. for 20 h ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4FDJUS Patent