Compile Data Set for Download or QSAR
Found 91 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 1423
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322158(2-(3-(4-((1H-indazol-5-yl)amino)-6-(4-methylpipera...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322158(2-(3-(4-((1H-indazol-5-yl)amino)-6-(4-methylpipera...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322152((R)-2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl...)copy SMILES
Affinity DataKi:  20nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322153(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322155(US10183931, SLx-2119 | US10696660, SLx-2119 | US11...)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322152((R)-2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl...)copy SMILES
Affinity DataKi:  70nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322154(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322157(2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl)phe...)copy SMILEScopy InChI
Affinity DataKi:  170nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322159((R)-2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl...)copy SMILEScopy InChI
Affinity DataKi:  180nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322154(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322155(US10183931, SLx-2119 | US10696660, SLx-2119 | US11...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322159((R)-2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl...)copy SMILEScopy InChI
Affinity DataKi:  870nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322153(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)copy SMILEScopy InChI
Affinity DataKi:  2.01E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322176(US10183931, Example 176 | US10696660, Example 176 ...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322165(US10183931, Example 166 | US10696660, Example 166 ...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322167(US10183931, Example 168 | US10696660, Example 168 ...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322153(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322174(N-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322172(US10183931, Example 173 | US10696660, Example 173 ...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322162(2-(3-(4-((1H-indazol-5-yl)amino)-6-(piperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322182(N-(2-(3-(2-(isopropylamino)ethoxy)phenyl)pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322164(US10183931, Example 165 | US10696660, Example 165 ...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322163(US10183931, Example 164 | US10696660, Example 164 ...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322166(US10183931, Example 167 | US10696660, Example 167 ...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322160(2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322154(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322169(US10183931, Example 170 | US10696660, Example 170 ...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322161(US10183931, Example 163 | US10696660, Example 163 ...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322170(US10183931, Example 171 | US10696660, Example 171 ...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322184(N-(2-(3-methoxyphenyl)-6-(piperazin-1-yl)pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322171(US10183931, Example 172 | US10696660, Example 172 ...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322173(US10183931, Example 174 | US10696660, Example 174 ...)copy SMILEScopy InChI
Affinity DataIC50: 191nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322184(N-(2-(3-methoxyphenyl)-6-(piperazin-1-yl)pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322158(2-(3-(4-((1H-indazol-5-yl)amino)-6-(4-methylpipera...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322181(US10183931, Example 179 | US10696660, Example 179 ...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322158(2-(3-(4-((1H-indazol-5-yl)amino)-6-(4-methylpipera...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322183(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl)-N-(pi...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322185(US10183931, Example 180 | US10696660, Example 180 ...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322187(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl)-N-(1,...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322158(2-(3-(4-((1H-indazol-5-yl)amino)-6-(4-methylpipera...)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322175(US10183931, Example 175 | US10696660, Example 175 ...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322152((R)-2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl...)copy SMILES
Affinity DataIC50: 540nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322179(US10183931, Example 178 | US10696660, Example 178 ...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322153(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322180(N-(2-(4-(1-aminoethyl)phenyl)pyrimidin-4-yl)-1H-in...)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322158(2-(3-(4-((1H-indazol-5-yl)amino)-6-(4-methylpipera...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322186(N-(6-(2-(dimethylamino)ethoxy)-2-(3-methoxyphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon Corporation, LLC

US Patent
LigandPNGBDBM322155(US10183931, SLx-2119 | US10696660, SLx-2119 | US11...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0B04US Patent
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