Compile Data Set for Download or QSAR
Found 173 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 1803
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341016(1-(5-Bromo-2-{[(3S)-3-[(4-methylpiperazin-1-yl)met...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341129(N-(4-Fluorophenyl)-1-{4-hydroxy-5-methoxy-2-[(3S)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341098(1-{4-Hydroxy-5-methoxy-2-[(3S)-3-[(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341040(1-(5-Chloro-2-{[(3S)-3-[(4-methylpiperazin-1-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341126(1-{4-Hydroxy-5-methoxy-2-[(3S)-3-[(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM340977(N-(4-Hydroxyphenyl)-N-(4-methylphenyl)-1-(6-{[(3S)...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM340980(N-(4-Fluorophenyl)-N-(4-hydroxyphenyl)-1-(6-{[(3S)...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341037(N-(4-Hydroxyphenyl)-5-methyl-N-(1-methyl-1H-indol-...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341032(N-(4-Chlorophenyl)-N-(4-hydroxyphenyl)-5-methyl-1-...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341024(1-(5-Chloro-4-fluoro-2-{[(3S)-3-[(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM340986(N,N-bis(4-Hydroxyphenyl)-1-(6-{[(3S)-3-[(4-methylp...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341030(N,N-bis(4-Hydroxyphenyl)-5-methyl-1-(6-{[(3S)-3-[(...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM340982(N-(4-Hydroxyphenyl)-N-(1H-indol-5-yl)-1-(6-{[(3S)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341043(N-(4-Hydroxyphenyl)-5-methyl-N-(4-methylphenyl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341019(1-(5-Chloro-2-{[(3S)-3-[(4-methylpiperazin-1-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341020(1-(5-Chloro-2-{[(3S)-3-[(4-methylpiperazin-1-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341104(1-{2-[(3S)-3-(Hydroxymethyl)-1,2,3,4-tetrahydroiso...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341036(1-(5-Chloro-2-{[(3S)-3-[(4-methylpiperazin-1-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341133(N-(4-Hydroxyphenyl)-1-{5-methoxy-2-[(3S)-3-[(4-met...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341130(1-{4-Hydroxy-5-methoxy-2-[(3S)-3-[(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341034(N-(4-Hydroxyphenyl)-N-(1H-indol-5-yl)-5-methyl-1-(...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM340978(N-Butyl-N-(4-hydroxyphenyl)-1-(6-{[(3S)-3-[(4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341057(N-(4-Hydroxyphenyl)-5-methyl-N-(1-methyl-1H-indol-...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341018(1-(5-Chloro-2-{[(3S)-3-[(4-methylpiperazin-1-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341132(N-Cyclohexyl-1-{4-hydroxy-5-methoxy-2-[(3S)-3-[(4-...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341047(N-(1-Ethyl-1H-indol-5-yl)-N-(4-hydroxyphenyl)-1-(6...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341023(1-(5-Chloro-4-fluoro-2-{[(3S)-3-[(4-methylpiperazi...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341000(N-(3,4-Difluorophenyl)-N-(4-hydroxyphenyl)-1-(6-{[...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341010(1-(5-Chloro-2-{[(3S)-3-[(4-methylpiperazin-1-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341038(1-(5-Chloro-2-{[(3S)-3-[(4-methylpiperazin-1-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341033(1-(5-Chloro-2-{[(3S)-3-[(4-methylpiperazin-1-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM340997(N-(3-Fluoro-4-methylphenyl)-N-(4-hydroxyphenyl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM340976(N-(4-Chlorophenyl)-N-(4-hydroxyphenyl)-1-(6-{[(3S)...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341122(1-{4-Hydroxy-5-methoxy-2-[(3S)-3-[(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341067(N-(4-Hydroxyphenyl)-5-methyl-N-(1-methyl-1H-indol-...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341012(1-(5-Chloro-2-{[(3S)-3-[(4-methylpiperazin-1-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341044(N-(3-Fluoro-4-hydroxyphenyl)-N-(1-methyl-1H-indol-...)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341108(1-{4-Hydroxy-5-methoxy-2-[(3S)-3-(piperidin-1-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341042(1-(5-Chloro-2-{[(3S)-3-[(dimethylamino)methyl]-3,4...)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341011(1-(5-Chloro-2-{[(3S)-3-[(4-methylpiperazin-1-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM340990(N-(4-Hydroxyphenyl)-N-(1-methyl-1H-indol-5-yl)-1-(...)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341123(N-Butyl-1-{4-hydroxy-5-methoxy-2-[(3S)-3-[(4-methy...)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341031(N-(4-Fluorophenyl)-N-(4-hydroxyphenyl)-5-methyl-1-...)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341027(1-(5-Bromo-2-{[(3S)-3-[(4-cyclopentylpiperazin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM340989(N-(1-Benzofuran-5-yl)-N-(4-hydroxyphenyl)-1-(6-{[(...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM340996(N-(4-Hydroxyphenyl)-1-(6-{[(3S)-3-[(4-methylpipera...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341113(1-{4-Hydroxy-5-methoxy-2-[(3S)-3-[(4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341048(N-(4-Hydroxyphenyl)-1-(6-{[(3S)-3-[(4-methylpipera...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM341021(1-(5-Chloro-2-{[(3S)-3-[(4-methylpiperazin-1-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent
LigandPNGBDBM340988(N-(1-Benzothiophen-5-yl)-N-(4-hydroxyphenyl)-1-(6-...)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72KJFUS Patent
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