Found 12 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 2151 TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 0.300nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 0.400nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
3D Structure (crystal)TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 0.5nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 1.30nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 1.40nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 5.70nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 13nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 13nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 28nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 44nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 70nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Alectos Therapeutics, Inc.; Merck Sharp & Dohme Corp.
US Patent
Affinity DataKi: 164nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
