Compile Data Set for Download or QSAR
Found 66 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 2652
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22955(4-methoxyphenyl 2-{1-[(4-chlorophenyl)carbonyl]-5-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22962(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 50nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School of Medicine

LigandPNGBDBM22955(4-methoxyphenyl 2-{1-[(4-chlorophenyl)carbonyl]-5-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMT: 2°CAssay Description:Inhibition assays in triplicate were performed by preincubating enzyme (60-80 nM) and inhibitors (0-5 mM) for 20 min at 25°C followed by the add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)copy SMILEScopy InChI
Affinity DataIC50: 50nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22967(2-phenylethyl 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)copy SMILEScopy InChI
Affinity DataIC50: 50nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22959(CHEMBL96954 | Indomethacin derivative, 12 | pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 50nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22961(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 60nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22973(CHEMBL149213 | Meclofenamic acid derivative, 25 | ...)copy SMILEScopy InChI
Affinity DataIC50: 60nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22957(2-(methylsulfanyl)phenyl 2-{1-[(4-chlorophenyl)car...)copy SMILEScopy InChI
Affinity DataIC50: 60nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22966(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 60nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22979(CHEMBL148629 | Meclofenamic acid derivative, 31 | ...)copy SMILEScopy InChI
Affinity DataIC50: 70nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22958(4-fluorophenyl 2-{1-[(4-chlorophenyl)carbonyl]-5-m...)copy SMILEScopy InChI
Affinity DataIC50: 75nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22954(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 120nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22960(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 120nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School of Medicine

LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)copy SMILEScopy InChI
Affinity DataIC50: 130nMT: 2°CAssay Description:Inhibition assays in triplicate were performed by preincubating enzyme (60-80 nM) and inhibitors (0-5 mM) for 20 min at 25°C followed by the add...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22975(2-[(2,6-dichloro-3-methylphenyl)amino]-N-(2-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 150nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22977(2-[(2,6-dichloro-3-methylphenyl)amino]-N-[(4-nitro...)copy SMILEScopy InChI
Affinity DataIC50: 200nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School of Medicine

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 210nMT: 2°CAssay Description:Inhibition assays in triplicate were performed by preincubating enzyme (60-80 nM) and inhibitors (0-5 mM) for 20 min at 25°C followed by the add...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22952(CHEMBL73572 | Indomethacin derivative, 5 | methyl ...)copy SMILEScopy InChI
Affinity DataIC50: 250nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22953(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 250nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School of Medicine

LigandPNGBDBM22966(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 260nMT: 2°CAssay Description:Inhibition assays in triplicate were performed by preincubating enzyme (60-80 nM) and inhibitors (0-5 mM) for 20 min at 25°C followed by the add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22956(4-(methylsulfanyl)phenyl 2-{1-[(4-chlorophenyl)car...)copy SMILEScopy InChI
Affinity DataIC50: 300nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School of Medicine

LigandPNGBDBM22975(2-[(2,6-dichloro-3-methylphenyl)amino]-N-(2-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 400nMT: 2°CAssay Description:Inhibition assays in triplicate were performed by preincubating enzyme (60-80 nM) and inhibitors (0-5 mM) for 20 min at 25°C followed by the add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22974(2-[(2,6-dichloro-3-methylphenyl)amino]-N-(2-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 600nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22951(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 700nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22965(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 700nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 750nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22974(2-[(2,6-dichloro-3-methylphenyl)amino]-N-(2-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 900nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22976(CHEMBL358222 | Meclofenamic acid derivative, 28 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22979(CHEMBL148629 | Meclofenamic acid derivative, 31 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22973(CHEMBL149213 | Meclofenamic acid derivative, 25 | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22959(CHEMBL96954 | Indomethacin derivative, 12 | pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22970(2-{1-[(4-bromophenyl)methyl]-5-methoxy-2-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22956(4-(methylsulfanyl)phenyl 2-{1-[(4-chlorophenyl)car...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22958(4-fluorophenyl 2-{1-[(4-chlorophenyl)carbonyl]-5-m...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School of Medicine

LigandPNGBDBM22970(2-{1-[(4-bromophenyl)methyl]-5-methoxy-2-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMT: 2°CAssay Description:Inhibition assays in triplicate were performed by preincubating enzyme (60-80 nM) and inhibitors (0-5 mM) for 20 min at 25°C followed by the add...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22978(2-[(2,6-dichloro-3-methylphenyl)amino]-N-(2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22978(2-[(2,6-dichloro-3-methylphenyl)amino]-N-(2-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22972(2-[(2,6-dichloro-3-methylphenyl)amino]-N-methylben...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22972(2-[(2,6-dichloro-3-methylphenyl)amino]-N-methylben...)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22964(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+4nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School of Medicine

LigandPNGBDBM22963(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+4nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22965(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22952(CHEMBL73572 | Indomethacin derivative, 5 | methyl ...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22977(2-[(2,6-dichloro-3-methylphenyl)amino]-N-[(4-nitro...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22961(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22960(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School of Medicine

LigandPNGBDBM22957(2-(methylsulfanyl)phenyl 2-{1-[(4-chlorophenyl)car...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+4nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP736GPubMed
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