Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 2857
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Monash University

LigandPNGBDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)copy SMILEScopy InChI
Affinity DataKi:  136nM ΔG°:  -38.8kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Monash University

LigandPNGBDBM25398(Bivalent derivative, 12e | N-[5-(2-{[6-({9-[(2R,3R...)copy SMILEScopy InChI
Affinity DataKi:  311nM ΔG°:  -36.8kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3554PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Monash University

LigandPNGBDBM25396(Bivalent derivative, 12c | N-[5-(2-{[4-({9-[(2R,3R...)copy SMILEScopy InChI
Affinity DataKi:  863nM ΔG°:  -34.3kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3554PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Monash University

LigandPNGBDBM25399(Bivalent derivative, 18 | N-[5-(1-{9-[(2R,3R,4S,5R...)copy SMILEScopy InChI
Affinity DataKi:  2.30E+3nM ΔG°:  -31.9kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3554PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Monash University

LigandPNGBDBM25397((2R,3R,4S,5R)-2-{6-[(4-{[2-(3-amino-4-hydroxypheny...)copy SMILEScopy InChI
Affinity DataKi:  4.31E+3nM ΔG°:  -30.3kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3554PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Monash University

LigandPNGBDBM25394(Bivalent derivative, 12a | N-[5-(2-{[2-({9-[(2R,3R...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3554PubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Monash University

LigandPNGBDBM25395((2R,3R,4S,5R)-2-{6-[(2-{[2-(3-amino-4-hydroxypheny...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/molepH: 7.4 T: 2°CAssay Description:The displacement of [125I]-(-)iodopindolol binding from the beta2AR was determined using DDT1 MF-2 cell membranes. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3554PubMed