Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 2979
LigandPNGBDBM26555(2-{[4-(but-2-yn-1-ylamino)benzene]sulfonyl}ethane-...)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair
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BindingDB Entry DOI: 10.7270/Q2930RH8PubMed
LigandPNGBDBM26556(3-{[4-(but-2-yn-1-ylamino)benzene]sulfonyl}propane...)copy SMILEScopy InChI
Affinity DataKi:  4.5nM ΔG°:  -47.2kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930RH8PubMed
LigandPNGBDBM26553(2-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}ethane-1-...)copy SMILEScopy InChI
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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BindingDB Entry DOI: 10.7270/Q2930RH8PubMed
LigandPNGBDBM26554(3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1...)copy SMILEScopy InChI
Affinity DataKi:  10nM ΔG°:  -45.2kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair
LigandPNGBDBM26550(2-{[4-(but-2-yn-1-yloxy)benzene](methyl)sulfonamid...)copy SMILEScopy InChI
Affinity DataKi:  10nM ΔG°:  -45.2kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930RH8PubMed
LigandPNGBDBM26559(3-{[4-(but-2-yn-1-ylamino)benzene]sulfonyl}cyclohe...)copy SMILEScopy InChI
Affinity DataKi:  17nM ΔG°:  -43.9kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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BindingDB Entry DOI: 10.7270/Q2930RH8PubMed
LigandPNGBDBM26543((3R)-1-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}pyrr...)copy SMILEScopy InChI
Affinity DataKi:  28nM ΔG°:  -42.7kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930RH8PubMed
LigandPNGBDBM26558(3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}cyclohexa...)copy SMILEScopy InChI
Affinity DataKi:  30nM ΔG°:  -42.5kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930RH8PubMed
LigandPNGBDBM26557(3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}cyclopent...)copy SMILEScopy InChI
Affinity DataKi:  50nM ΔG°:  -41.3kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930RH8PubMed