Compile Data Set for Download or QSAR
Found 14 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50000536
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50006990(CHEMBL299499 | N-Adamantan-1-yl-N'-(4-iodo-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N802DPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50006986(CHEMBL442356 | N-Adamantan-1-yl-N'-(4-fluoro-2-met...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N802DPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50006991(CHEMBL55970 | N-Adamantan-1-yl-N'-(2-iodo-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N802DPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50006983(CHEMBL55873 | N-Adamantan-1-yl-N'-(4-methoxy-2-met...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N802DPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50006988(CHEMBL54407 | N-Adamantan-1-yl-N'-(3-methoxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N802DPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50006987(CHEMBL55769 | N-Adamantan-1-yl-N'-(3-iodo-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N802DPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50006993(CHEMBL293059 | N-Adamantan-1-yl-N'-(2-fluoro-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N802DPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50006989(CHEMBL292450 | N-Adamantan-1-yl-N'-(4-fluoro-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N802DPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50006992(CHEMBL292668 | N-Adamantan-1-yl-N'-(4-methoxy-phen...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N802DPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50006984(CHEMBL413257 | N-Adamantan-1-yl-N'-(3-fluoro-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N802DPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM50006985(CHEMBL301623 | N-Adamantan-1-yl-N'-(2-methoxy-phen...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N802DPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N802DPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institutions

Curated by ChEMBL
LigandPNGBDBM81924((R)-3-(1-Propyl-piperidin-3-yl)-phenol | 3PPP(+/-)...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Displacement of [3H]-DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N802DPubMed