Compile Data Set for Download or QSAR
Found 62 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50009566
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50105834(CHEMBL3597594)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50105834(CHEMBL3597594)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529958(CHEMBL4472693)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529958(CHEMBL4472693)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529965(CHEMBL4441707)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529965(CHEMBL4441707)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529959(CHEMBL4551786)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529959(CHEMBL4551786)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529954(CHEMBL4446275)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529954(CHEMBL4446275)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529974(CHEMBL4544729)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529974(CHEMBL4544729)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529989(CHEMBL4542890)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529989(CHEMBL4542890)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529972(CHEMBL4472416)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529972(CHEMBL4472416)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529971(CHEMBL4464022)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529971(CHEMBL4464022)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529955(CHEMBL4475143)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529955(CHEMBL4475143)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529956(CHEMBL4551238)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529956(CHEMBL4551238)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529987(CHEMBL4448788)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529987(CHEMBL4448788)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529983(CHEMBL4441964)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529983(CHEMBL4441964)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529984(CHEMBL4448804)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529984(CHEMBL4448804)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50105838(FENOBAM)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50105838(FENOBAM)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529976(CHEMBL4452522)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529976(CHEMBL4452522)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50122758(2-methyl-4-(pyridin-3-ylethynyl)thiazole | 3-(2-(2...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50122758(2-methyl-4-(pyridin-3-ylethynyl)thiazole | 3-(2-(2...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529980(CHEMBL4535926)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529980(CHEMBL4535926)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529990(CHEMBL4456792)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529990(CHEMBL4456792)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529962(CHEMBL4539036)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529962(CHEMBL4539036)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529961(CHEMBL4483689)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529961(CHEMBL4483689)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529991(CHEMBL4567923)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529991(CHEMBL4567923)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529960(CHEMBL4520868)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529960(CHEMBL4520868)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529978(CHEMBL4592284)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati S.p.A.

Curated by ChEMBL
LigandPNGBDBM50529978(CHEMBL4592284)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO-TREx cell membranes assessed as reduction in quisqualate-induced Ca2+ mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24171JFPubMed
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