Compile Data Set for Download or QSAR
Found 14 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50011806
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110577(2-(2-((dimethylamino)methyl)phenylthio)-5-iodoanil...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110782(CHEMBL429065 | [5-Iodo-2-(2-methylaminomethyl-phen...)copy SMILEScopy InChI
Affinity DataKi:  0.980nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110780(5-Iodo-2-(2-methylaminomethyl-phenylsulfanyl)-phen...)copy SMILEScopy InChI
Affinity DataKi:  1.25nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110777(5-Bromo-2-(2-methylaminomethyl-phenylsulfanyl)-phe...)copy SMILEScopy InChI
Affinity DataKi:  1.49nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-((dimethylamino)methyl)phenylthio)-5-methylan...)copy SMILEScopy InChI
Affinity DataKi:  1.65nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50073438(CHEMBL278165 | [5-Bromo-2-(2-dimethylaminomethyl-p...)copy SMILEScopy InChI
Affinity DataKi:  1.92nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110781(5-Bromo-2-(2-dimethylaminomethyl-phenylsulfanyl)-p...)copy SMILEScopy InChI
Affinity DataKi:  2.23nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110784(CHEMBL284002 | [2-(4-Iodo-2-methoxymethyl-phenylsu...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110786(CHEMBL22259 | [2-(4-Bromo-2-methoxymethyl-phenylsu...)copy SMILEScopy InChI
Affinity DataKi:  2.75nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110783(CHEMBL22743 | [2-(2-Dimethylaminomethyl-phenylsulf...)copy SMILEScopy InChI
Affinity DataKi:  7.96nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110787(2-(2-{[(2-Fluoro-ethyl)-methyl-amino]-methyl}-phen...)copy SMILEScopy InChI
Affinity DataKi:  19.3nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110778(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-iodo...)copy SMILEScopy InChI
Affinity DataKi:  53.3nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110785(2-(4-Fluoro-2-formyl-phenylsulfanyl)-N,N-dimethyl-...)copy SMILEScopy InChI
Affinity DataKi:  695nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
INSERM

Curated by ChEMBL
LigandPNGBDBM50110779(2-(4-Bromo-2-formyl-phenylsulfanyl)-N,N-dimethyl-b...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8M15PubMed