Compile Data Set for Download or QSAR
Found 13 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50012212
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116208(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  259nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116204(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  384nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50029275(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)copy SMILEScopy InChI
Affinity DataKi:  413nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116206((S)-1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethy...)copy SMILEScopy InChI
Affinity DataKi:  592nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116209(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  615nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116205(1-(5-Bromo-thiophen-2-ylmethyl)-4-(2-methoxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  757nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116201(CHEMBL302495 | {5-[4-(2-Methoxy-phenyl)-piperazin-...)copy SMILEScopy InChI
Affinity DataKi:  1.06E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116212(5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-thio...)copy SMILEScopy InChI
Affinity DataKi:  1.88E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116202(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi:  2.57E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116203(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116200(CHEMBL303485 | {5-[4-(2-Propoxy-phenyl)-piperazin-...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116207(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50116210(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DJ5F04PubMed