Compile Data Set for Download or QSAR
Found 31 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50012290
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50098551((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50098549((6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116963(2a-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116967(2-[2-(6-Bromo-indol-1-yl)-ethyl]-decahydro-pyrido[...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116960(2-[2-(6-Trifluoromethyl-indol-1-yl)-ethyl]-decahyd...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116971(6-Bromo-1-[2-(4-cyclopropylmethyl-[1,4]diazepan-1-...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116970(6-Bromo-1-[2-(4-cyclopentyl-[1,4]diazepan-1-yl)-et...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116951(2-[2-(6-Chloro-indol-1-yl)-ethyl]-decahydro-pyrido...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116943(6-Bromo-1-[2-(4-isopropyl-[1,4]diazepan-1-yl)-ethy...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116964(6-Bromo-1-[2-(4-cyclopropyl-[1,4]diazepan-1-yl)-et...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116944(6-Bromo-1-[2-(4-cyclohexyl-[1,4]diazepan-1-yl)-eth...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116966(1-[2-(4-Methyl-[1,4]diazepan-1-yl)-ethyl]-6-triflu...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116958(6-Bromo-1-[2-(4-methyl-[1,4]diazepan-1-yl)-ethyl]-...)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50098550(3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin...)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116965(6-Chloro-1-[2-(4-methyl-[1,4]diazepan-1-yl)-ethyl]...)copy SMILEScopy InChI
Affinity DataKi:  34nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116950(6-Bromo-1-[2-(4-isobutyl-[1,4]diazepan-1-yl)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116956(6-Isopropenyl-1-[2-(4-methyl-[1,4]diazepan-1-yl)-e...)copy SMILEScopy InChI
Affinity DataKi:  70nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116952(2-[2-(6-Bromo-indol-1-yl)-ethyl]-octahydro-pyrido[...)copy SMILEScopy InChI
Affinity DataKi:  70nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116955(5-Bromo-1-[2-(4-methyl-[1,4]diazepan-1-yl)-ethyl]-...)copy SMILEScopy InChI
Affinity DataKi:  88nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116948(1-[2-(4-Methyl-[1,4]diazepan-1-yl)-ethyl]-6-vinyl-...)copy SMILEScopy InChI
Affinity DataKi:  109nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116962(1-[2-(4-Methyl-[1,4]diazepan-1-yl)-ethyl]-6-thioph...)copy SMILEScopy InChI
Affinity DataKi:  109nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116945(6-Methyl-1-[2-(4-methyl-[1,4]diazepan-1-yl)-ethyl]...)copy SMILEScopy InChI
Affinity DataKi:  125nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116959(1-[2-(4-Methyl-[1,4]diazepan-1-yl)-ethyl]-6-nitro-...)copy SMILEScopy InChI
Affinity DataKi:  139nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116947(6-Ethynyl-1-[2-(4-methyl-[1,4]diazepan-1-yl)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116949(6-Isopropyl-1-[2-(4-methyl-[1,4]diazepan-1-yl)-eth...)copy SMILEScopy InChI
Affinity DataKi:  145nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116968(2-[2-(5-Bromo-indol-1-yl)-ethyl]-octahydro-pyrido[...)copy SMILEScopy InChI
Affinity DataKi:  158nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116961(6-Bromo-1-{2-[4-(2,2-dimethyl-propyl)-[1,4]diazepa...)copy SMILEScopy InChI
Affinity DataKi:  163nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116946(6-Ethyl-1-[2-(4-methyl-[1,4]diazepan-1-yl)-ethyl]-...)copy SMILEScopy InChI
Affinity DataKi:  166nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116954(6-Benzyloxy-1-[2-(4-methyl-[1,4]diazepan-1-yl)-eth...)copy SMILEScopy InChI
Affinity DataKi:  182nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116953(6-Fluoro-1-[2-(4-methyl-[1,4]diazepan-1-yl)-ethyl]...)copy SMILEScopy InChI
Affinity DataKi:  288nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
NPS Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50116957(6-Methoxy-1-[2-(4-methyl-[1,4]diazepan-1-yl)-ethyl...)copy SMILEScopy InChI
Affinity DataKi:  1.57E+3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor on HEK293 cells using radioligand [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JTZPubMed