Compile Data Set for Download or QSAR
Found 15 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50012431
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557581(CHEMBL4755060)copy SMILES
Affinity DataIC50: 64nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557580(CHEMBL4796831)copy SMILES
Affinity DataIC50: 141nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557576(CHEMBL4763348)copy SMILES
Affinity DataIC50: 142nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557575(CHEMBL4751020)copy SMILES
Affinity DataIC50: 376nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557578(CHEMBL4760459)copy SMILES
Affinity DataIC50: 780nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557577(CHEMBL4795293)copy SMILES
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557571(CHEMBL4789884)copy SMILES
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557579(CHEMBL4753324)copy SMILES
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557572(CHEMBL4792690)copy SMILES
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557573(CHEMBL4763530)copy SMILES
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)copy SMILEScopy InChI
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557574(CHEMBL4787114)copy SMILES
Affinity DataIC50: 3.14E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557583(CHEMBL4763722)copy SMILES
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557582(CHEMBL4762617)copy SMILES
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed