Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50027877
TargetAromatase(Homo sapiens (Human))
Universidade de Coimbra

Curated by ChEMBL
LigandPNGBDBM50254017(6-((4-fluorophenyl)(1H-imidazol-1-yl)methyl)benzo[...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by Lineweaver-Burk plot in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9080PubMed
TargetAromatase(Homo sapiens (Human))
Universidade de Coimbra

Curated by ChEMBL
LigandPNGBDBM13061(4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitr...)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by Lineweaver-Burk plot in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9080PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
Universidade de Coimbra

Curated by ChEMBL
LigandPNGBDBM50254016(6-(benzo[d][1,3]dioxol-5-yl(1H-imidazol-1-yl)methy...)copy SMILEScopy InChI
Affinity DataKi:  5.60nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by Lineweaver-Burk plot in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9080PubMed
TargetAromatase(Homo sapiens (Human))
Universidade de Coimbra

Curated by ChEMBL
LigandPNGBDBM50254015(1-(2-(3,4-dichlorophenylthio)-2-(4-methoxyphenyl)e...)copy SMILEScopy InChI
Affinity DataKi:  6.5nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by Lineweaver-Burk plot in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9080PubMed
TargetAromatase(Homo sapiens (Human))
Universidade de Coimbra

Curated by ChEMBL
LigandPNGBDBM50265438(6-((1H-imidazol-1-yl)(4-methoxyphenyl)methyl)benzo...)copy SMILEScopy InChI
Affinity DataKi:  13.1nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by Lineweaver-Burk plot in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9080PubMed
TargetAromatase(Homo sapiens (Human))
Universidade de Coimbra

Curated by ChEMBL
LigandPNGBDBM50265464(4-(5-(4-chlorophenyl)-4-(pyridin-3-yl)-1H-imidazol...)copy SMILEScopy InChI
Affinity DataKi:  15.1nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by Lineweaver-Burk plot in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9080PubMed
TargetAromatase(Homo sapiens (Human))
Universidade de Coimbra

Curated by ChEMBL
LigandPNGBDBM50265443(6-chloro-2-methoxy-N-(pyridin-3-yl)acridin-9-amine...)copy SMILEScopy InChI
Affinity DataKi:  25.5nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by Lineweaver-Burk plot in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9080PubMed
TargetAromatase(Homo sapiens (Human))
Universidade de Coimbra

Curated by ChEMBL
LigandPNGBDBM50265440(3-(2-(1H-imidazol-1-yl)ethyl)-6-chloro-5-(1H-imida...)copy SMILEScopy InChI
Affinity DataKi:  33.4nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by Lineweaver-Burk plot in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9080PubMed
TargetAromatase(Homo sapiens (Human))
Universidade de Coimbra

Curated by ChEMBL
LigandPNGBDBM50265439(3-((1H-imidazol-1-yl)methyl)-1-benzyl-5-nitro-1H-i...)copy SMILEScopy InChI
Affinity DataKi:  52.7nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by Lineweaver-Burk plot in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9080PubMed