Compile Data Set for Download or QSAR
Found 23 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50030919
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304049(1-[3beta-(4-Chloro-phenyl)tropane-2beta-carbonyl-o...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304053(CHEMBL595677 | methyl 8-methyl-3-(4-(thiophen-3-yl...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304045(CHEMBL608703 | methyl 3-(4-chlorophenyl)-8-methyl-...)copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304046(1-[3beta-(4-Chloro-phenyl)tropane-2beta-carbonyl-o...)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM22166(3-(4-iodophenyl)tropane-2-carboxylic acid methyl e...)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304047(1-[3beta-(4-Chlorophenyl)tropane-2beta-carbonyl-ox...)copy SMILEScopy InChI
Affinity DataKi:  5.5nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304048(1-[3beta-(4-Chlorophenyl)tropane-2beta-carbonyl-am...)copy SMILEScopy InChI
Affinity DataKi:  6.60nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304050(1-[3beta-(4-Chloro-phenyl)tropane-2beta-carbonyl-o...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304051(1-[3beta-(4-Chlorophenyl)tropane-2beta-carbonyl-am...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304052(1-[3beta-(4-Chlorophenyl)tropane-2beta-carbonyl-am...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304055(1,4-Di[3-(4-thiophene-3-yl-phenyl)tropane-2-carbon...)copy SMILEScopy InChI
Affinity DataKi:  93nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304054(1-[3beta-(4-Thiophene-3-yl-phenyl)tropane-2beta-ca...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304056(1-[3beta-(4-Chlorophenyl)tropane-2beta-carbonyl-am...)copy SMILEScopy InChI
Affinity DataKi:  180nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304057(1,4-Di[3beta-(4-thiophene-3-yl-phenyl)tropane-2bet...)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304058(1,3-Di[3-(4-thiophene-3-yl-phenyl)tropane-2-carbon...)copy SMILEScopy InChI
Affinity DataKi:  230nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304059(1,10-Di[3beta-(4-thiophene-3-yl-phenyl)tropane-2bc...)copy SMILEScopy InChI
Affinity DataKi:  350nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304062(1,6-Di[3beta-(4-thiophene-3-yl-phenyl)tropane-2bet...)copy SMILEScopy InChI
Affinity DataKi:  540nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304061(1,8-Di[3beta-(4-thiophene-3-yl-phenyl)tropane-2bet...)copy SMILEScopy InChI
Affinity DataKi:  690nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304063(1,4-Di[3beta-(4-chlorophenyl)tropane-2beta-carbony...)copy SMILEScopy InChI
Affinity DataKi:  690nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304060(1-[3beta-(4-Thiophene-3-yl-phenyl)tropane-2beta-ca...)copy SMILEScopy InChI
Affinity DataKi:  710nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304064(1-[3beta-(4-Thiophene-3-yl-phenyl)tropane-2beta-ca...)copy SMILEScopy InChI
Affinity DataKi:  800nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304066(CHEMBL595539 | trans-1,4-Di[3beta-(4-chlorophenyl)...)copy SMILEScopy InChI
Affinity DataKi:  890nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304065(CHEMBL594388 | trans-1,4-Di[3beta-(4-thiophene-3-y...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749Z2PubMed