Compile Data Set for Download or QSAR
Found 23 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50031598
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315980(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)copy SMILEScopy InChI
Affinity DataKi:  0.0650nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315979(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)copy SMILEScopy InChI
Affinity DataKi:  0.0860nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315985(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(methyl(phenyl...)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315981(3-(4-((1H-pyrazol-1-yl)methyl)-2-(naphthalen-1-ylm...)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315967(CHEMBL1092432 | N-(3,4-difluorophenylsulfonyl)-3-(...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315982(3-(4-((1H-pyrazol-1-yl)methyl)-2-phenethoxyphenyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315978(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)copy SMILEScopy InChI
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315984(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-phenoxyethoxy)...)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315975(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)copy SMILEScopy InChI
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315976(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)copy SMILEScopy InChI
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315977(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)copy SMILEScopy InChI
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315969(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315966(3-(4-((3-cyanophenoxy)methyl)-2-(2-(naphthalen-2-y...)copy SMILEScopy InChI
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315983(3-(4-((1H-pyrazol-1-yl)methyl)-2-(3-morpholinophen...)copy SMILEScopy InChI
Affinity DataKi:  0.540nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315974(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)copy SMILEScopy InChI
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315973(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315965(CHEMBL1092097 | N-(3,4-difluorophenylsulfonyl)-3-(...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315972(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315964(CHEMBL1090938 | N-(3,4-difluorophenylsulfonyl)-3-(...)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315970(CHEMBL1092267 | N-(4-((1H-pyrazol-1-yl)methyl)-2-(...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM35861(phenylpropanoic acid analogue, 5)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315968(3-(4-((1H-pyrazol-1-yl)methyl)-2-(2-(naphthalen-2-...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50315971(CHEMBL1091959 | N-(4-((1H-pyrazol-1-yl)methyl)-2-(...)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6099PubMed