Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50032575
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM50331290(CHEMBL1289953 | N-(3-aminopropyl)-2-(3-methylbenzy...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN459HPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM82302(5-BENZYLOXYTRYPTAMINE | 5-BZT | CAS_20776-45-8 | C...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN459HPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM50331285(2-(5-(benzyloxy)-2-methyl-1H-indol-3-yl)ethanamine...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN459HPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM50247069(2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 3.34E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN459HPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM50054758(CHEMBL357130 | [2-(5-Benzyloxy-1H-indol-3-yl)-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 5.63E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN459HPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM30853(2-(5-fluoranyl-1H-indol-3-yl)ethanamine;hydrochlor...)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN459HPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM82087(2-(5-methoxy-1H-indol-3-yl)ethanamine | 5-MT | 5-M...)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN459HPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM50331286(2-(5-chloro-1H-indol-3-yl)ethanamine | 5-Cl-T | CH...)copy SMILEScopy InChI
Affinity DataIC50: 2.15E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN459HPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM50331287(CHEMBL1289952 | ethyl 2-(5-(benzyloxy)-1H-indol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 2.16E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN459HPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM50331288(2-(5-bromo-1H-indol-3-yl)ethanamine | 5-Br-T | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 2.27E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN459HPubMed